The following ASP.NET controls are not compatible with partial-page updates, and are therefore not supported inside an UpdatePanel control:
- TreeView
- Menu controls.
- FileUpload controls.
- GridView and DetailsView controls when their EnableSorting And Paging property is set to true.
- Login, PasswordRecovery, ChangePassword, and CreateUserWizard controls whose contents have not been converted to editable templates.
- Validation controls
- It includes the BaseCompareValidator, BaseValidator, CompareValidator, CustomValidator, RangeValidator, RegularExpressionValidator, RequiredFieldValidator, and ValidationSummary control.
Also i come to know that u cant do a partial update inside a repeter control.